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US Longevity Laboratories · Dermatology-grade skincare

Skincare built on dermatological science, not trends.

Formulated and tested by US Longevity Laboratories, engineered for lasting results.

In-house laboratory

Formulation, testing, and release under one roof

$2M+ equipment

Advanced analytical instrumentation

Batch tested

Every lot verified against specification

Dermatology-grade

Developed using dermatological science

01Understanding your skin

The body's largest organ, and its most visible.

Skin is a layered, living system. Understanding its architecture is the foundation of any considered routine — and of every formula we develop.

Epidermis

≈ 0.05–1.5 mm

The outermost layer. Its surface, the stratum corneum, is a lattice of flattened cells held in a matrix of ceramides, cholesterol, and fatty acids — the structure most skincare is designed to support.

Dermis

≈ 1–4 mm

A dense connective layer of collagen and elastin fibers, blood vessels, and nerve endings. It gives skin its firmness, spring, and much of its visible texture.

Hypodermis

Variable

The deepest layer, composed largely of adipose tissue. It cushions underlying structures, stores energy, and helps insulate the body.

Macro photograph of human skin surface texture, luminous and dewy in warm beige tones

Fig. 1 — Surface micro-relief of the stratum corneum

F.01

Barrier protection

Limits water loss and helps keep environmental irritants and microbes out.

F.02

Temperature regulation

Adjusts blood flow and perspiration to help maintain core body temperature.

F.03

Sensation

Specialized receptors register touch, pressure, vibration, and temperature.

What thoughtful skincare can address

Cosmetic skincare works at the surface — supporting the barrier, improving hydration, and influencing how skin looks and feels over time. It can meaningfully improve the appearance of skin affected by aging, cumulative sun exposure, rough texture, and dryness.

  • Visible signs of aging
  • Daily sun exposure
  • Uneven texture
  • Dehydration & dryness

This site provides general skin health information and does not diagnose or treat any medical condition. Consult a licensed dermatologist for any skin concern.

Hands gently applying a drop of clear serum to the back of the hand in soft window light

Skin type, climate, and lifestyle vary widely. A licensed dermatologist can tailor a routine to the individual.

02What your skin needs

Six fundamentals. No shortcuts.

Beneath every trend is a short list of practices with consistent support in the dermatological literature. These are the principles our formulations are built around.

    01

    Daily SPF

    Ultraviolet exposure is the single largest external contributor to visible skin aging. A broad-spectrum sunscreen, applied every morning and reapplied with extended time outdoors, is the most well-supported step in any routine.

    02

    Gentle cleansing

    Cleansing should remove sunscreen, sebum, and pollutants without disrupting barrier lipids. Low-pH, sulfate-free formulas tend to leave skin comfortable rather than tight.

    03

    Barrier support

    The stratum corneum relies on a balance of ceramides, cholesterol, and free fatty acids. Replenishing these lipids helps skin retain water and stay resilient.

    04

    Antioxidants

    Compounds such as niacinamide, vitamin C derivatives, and polyphenols help neutralize free radicals generated by UV and pollution, complementing — not replacing — sunscreen.

    05

    Peptides

    Short chains of amino acids used in cosmetic formulations to support the look of firmness and smoothness. They are well tolerated and pair easily with other actives.

    06

    Hydration

    Humectants like glycerin and hyaluronic acid draw water into the upper layers of skin, while emollients and occlusives help keep it there.

03Find your ritual

Sixty seconds to your routine.

Answer three questions and we'll match you to the two-to-four formulas from our collection that fit your skin — the same approach a SkinCeuticals routine builder takes, with none of the upsell.

Question 1 / 3

What would you most like to improve?

04The collection

A five-step system for resilient, luminous skin.

Our house line is intentionally edited: five formulas that cover the fundamentals with clinical-grade research standards and nothing superfluous.

Not sure where to start? Take the sixty-second ritual quiz and we'll match you to the right formulas.

Developed
Using dermatological science and published ingredient research.
Tested
At the US Longevity Laboratories facility, batch by batch.
Formulated
Around longevity-focused, barrier-supporting ingredients.
Frosted glass cleanser pump bottle with champagne cap on white marble, photographed from above
Clinical overlay

C₃H₈O₃

Glycerin + Colloidal Oat

Humectant hydration and lipid-barrier comfort during cleansing.

No. 01

Barrier Cleanser

Low-pH gel cleanser · 150 mL

A gentle, sulfate-free gel that lifts sunscreen, sebum, and daily particulate without stripping the skin's natural lipids.

Clear glass dropper bottle of golden serum on white satin with a single droplet beside it
Clinical overlay

C₆H₆N₂O

Niacinamide + Resveratrol

Antioxidant support and a more even-looking tone.

No. 02

Longevity Serum

Antioxidant peptide serum · 30 mL

A lightweight daily serum pairing antioxidants with signal peptides to support the look of firm, even-toned, resilient skin.

Open white cream jar with a smooth swirl of ivory moisturizer and a champagne lid on marble
Clinical overlay

C₃₀H₆₂

Ceramides + Squalane

Replenishes barrier lipids and reduces the feel of dryness.

No. 03

Barrier Moisturizer

Ceramide cream · 50 mL

A skin-identical lipid cream built on the ceramide, cholesterol, and fatty-acid ratio found in a healthy stratum corneum.

Matte white sunscreen tube with champagne cap and a smear of mineral lotion on ivory linen in sunlight
Clinical overlay

ZnO

Zinc Oxide

Broad-spectrum UVA/UVB filtering for daily protection.

No. 04

Mineral SPF 40

Broad-spectrum mineral sunscreen · 50 mL

A sheer, non-nano zinc oxide fluid designed for daily wear, finishing soft and translucent on a wide range of skin tones.

Amber glass night treatment bottle with dropper on dark stone under soft moody light
Clinical overlay

C₁₈H₂₄O

Bakuchiol + Squalane

Supports the look of smoother texture, gentle enough for nightly use.

No. 05

Night Renewal Treatment

Overnight treatment oil · 30 mL

A botanical overnight treatment that works while you sleep to support the look of smoother texture and a well-rested complexion.

Hover or focus a product to view its key ingredient. Cosmetic products are intended to improve the appearance of skin; individual results vary.

Modern research microscope in a clean laboratory under focused lighting
The science behind it

Every formula passes through our own lab before it reaches yours.

Our house line is developed and verified in-house at US Longevity Laboratories — a facility equipped with advanced analytical instrumentation for research, formulation, and quality testing. That lets us control each stage of development rather than outsourcing it.

S.01

Ingredient qualification

Raw materials are reviewed against supplier certificates of analysis and checked for identity and purity on receipt.

S.02

Formulation development

Iterative bench formulation to balance active concentration, pH, texture, and compatibility across ingredients.

S.03

Analytical verification

Instrumental analysis confirms composition and consistency from pilot batch to production run.

S.04

Stability & compatibility

Accelerated and real-time stability studies assess how each formula holds up across temperature, light, and packaging.

Glass pipette dispensing clear liquid into a laboratory beaker

Learn more about the lab at uslongevitylabs.com.

05White label manufacturing

Bring your brand to market with dermatology-grade skincare.

Every brand wants a credible, science-backed skincare line, but few can build the formulation, sourcing, and testing infrastructure themselves. US Longevity Laboratories handles all of it — formulation, ingredient sourcing, lab testing, and packaging — so you can launch your own branded line without building a lab.

Clean cosmetic manufacturing room with rows of blank frosted glass bottles on a stainless steel line
  • Technical spec

    • Stock formulas ready for your branding, or fully custom development
    • Brief-to-bench process: target claims, texture, sensorial profile
    • Iterative sampling rounds with documented formula revisions
    • Ingredient sourcing from qualified, documented suppliers
06The network

Part of a global luxury and longevity network.

Dermatologists.com.ai sits within a family of research, care, and lifestyle platforms. Explore each below.

Lab & longevity science

N.01 · 7 platforms

Skin, hair & body care

N.02 · 8 platforms

These platforms operate together under US Longevity Laboratories, bringing research-backed longevity science and luxury lifestyle content to a global audience.

07Questions

Frequently asked.

Clear glass skincare bottle on a dark stone plinth lit by a thin line of champagne light
Begin

Whether you're looking for visible results or ready to bring your own dermatology-grade line to life, we're ready to talk.